Year:2022   Volume: 4   Issue: 1   Area: Psychology

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  3. ID: 420

Abdul Razzaq Jabr AL MAJIDI, Rafia S. FATHI, Rehab S. RAMADHAN

A POSSIBLE CORRELATION BETWEEN MYOSTATIN AND TESTOSTERONE AIDED BY GENETIC FACTORS ENHANCING ‎ATHLETIC PERFORMANCE AND MUSCLE RECOVERY

Background: multiple factors can affect athletic performance including nutrition, environmental, ‎physiological, physical fitness, and genetic factors. Hormonal factors such as testosterone, and ‎myostatin (MSTN) or GDF8 can be named to show significant effect on muscle growth and ‎recovery after intensive training. Illustrating the combined relationship between the latest factors ‎may help in developing efficient program for athletic care and exceled performance.‎ Methods: participation in this work came from 67 male divided into two groups of 35 endurance ‎and sprinters and 32 power athletes, with 36 females fall into two groups of 20 sprinters and 16 ‎power athletes. Testosterone and MSTN levels were measured in both genders before, and after ‎intensive training program followed by third measurement after 5 hours rest and recovery. The ‎MSTN gene was analyzed for the presence of genetic polymorphism using specific PCR ‎amplification.‎ Results: data obtained showed the presence of negative relationship between testosterone and ‎MSTN, whereas genetic analysis showed presence of three genotypes with different frequencies ‎each one of them affected MSTN with different rate ranging from normal production levels with ‎normal function to lack of function found in power athletes showing speedup muscle recovery and ‎higher muscle mass.‎ Conclusions: higher levels of testosterone reduced MSTN levels significantly showing negative ‎correlation between them. Low expression or production of nonfunctional MSTN protein enhanced ‎muscle recovery, higher muscle mass, and improved athletic performance.‎

Keywords: MSTN, Testosterone, Athletic Performance, Athletic Genes‎.

http://dx.doi.org/10.47832/2717-8293.15.32


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